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GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome

GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome

  • GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome
  • GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome
  • GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome
  • GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome
GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome
Product Details:
Place of Origin: Hubei, China
Brand Name: Bodybiological
Certification: ISO9001, SGS
Model Number: CAS: 98319-26-7
Payment & Shipping Terms:
Minimum Order Quantity: 10gram
Price: USD2/gram
Packaging Details: Foil bag
Delivery Time: Within 24 hours
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 100kg/month
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Detailed Product Description
Keywords: Tibolone Appearance: Yellow Powder
Shipping Method: FEDEX, TNT, DHL, UPS, HK EMS Payment Terms: Money Gram, Western Union, Bank Transfer
Export Market: USA, UK, Canada, Thailand, Brazil Purity: 99%
Policy: Reshipping Policy Brand: Bodybiological
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GMP Grade Fitness Building Tibolone Acetate for Menopausal Syndrome

 

Basic information:

 

Synonyms:LIVIELLA; LIVIAL
Quick Detail:
CAS: 5630-53-5
EINECS: 227-069-1
Molecular Formula: C21H28O2
Molecular weight: 312.45
Melting Point: 169°C
Character: White powder.
Delivery: Express courier.
Usage: Pharmaceutical material

 

Detailed information:

 

Tibolone (INN, USAN, BAN) (brand name Livial, Tibofem), also known as 7α-methylnoretynodrel,[1] is a synthetic steroid drug with estrogenic, progestogenic, and weak androgenic actions which was introduced in 1988 and is used widely in Europe, Asia, Australasia, and, with the exception of the United States (where it is not available), the rest of the world.[2][3][4][5] It is used mainly for treatment of endometriosis,[6] as well as hormone replacement therapy in post-menopausal women. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile.[7][8][9] It has also been investigated as a possible treatment for female sexual dysfunction.

 

Applications:

 

Tibolone possesses a complex pharmacology.[14] Its two major active metabolites, 3α-hydroxytibolone and 3β-hydroxytibolone, act as potent, fully activating agonists of the estrogen receptor (ER), with a high preference for ERα.[14][15][16] Tibolone and its metabolite Δ4-tibolone act as agonists of the progesterone and androgen receptors,[15] while 3α-hydroxytibolone and 3β-hydroxytibolone, conversely, act as antagonists of these receptors.[14] Lastly, tibolone, 3α-hydroxytibolone, and 3β-hydroxytibolone act as antagonists of the glucocorticoid and mineralocorticoid receptors, with preference for the mineralocorticoid receptor.[14]

Tibolone has tissue-selective estrogenic effects, with desirable effects in bone, the brain, and the vagina, and lack of undesirable action in the endometrium and breasts.[16] Its tissue selectivity is the result of metabolism, enzyme modulation (e.g., of estrogen sulfatase and estrogen sulfotransferase), and receptor modulation that vary in different target tissues, and differs mechanistically from that of selective estrogen receptor modulators (SERMs) such as tamoxifen, which produce their tissue-selectivity via means of modulation of the ER.[15][16] As such, to distinguish it from SERMs, tibolone has been described as a "selective tissue estrogenic activity regulator" (STEAR),[16] and also as a "selective estrogen enzyme modulator"

 

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Contact Details
Wuhan Body Biological Co.,Ltd

Contact Person: Clare

Tel: +8618271632602

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