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|Place of Origin:||Hubei, China|
|Minimum Order Quantity:||1kit|
|Packaging Details:||Foil bag|
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|Form:||White Freezed Powder||Shipping Way:||FEDEX, TNT, DHL, UPS, HK EMS|
|Payment Terms:||Money Gram, Western Union, Bank Transfer||MOQ:||1kit|
|Delivery Time:||Within 24 Hours After The Payment||Brand:||Bodybiological|
natural hgh supplements,
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Legal HGH Human Growth Hormone Peptide Follistatin in Freeze-Dried Powder
Synonyms:FST, FS, Activin-binding protein.
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:Lyophilized from a concentrated (1mg/ml) solution containing no additives.
Solubility:It is recommended to reconstitute the lyophilized Follistatin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Purity:Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Usage:These products are furnished for LABORATORY RESEARCH USE ONLY.They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals.
Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene. Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals.
It was initially isolated from follicular fluid and was identified as a protein fraction that inhibited follicle-stimulating hormone (FSH) secretion from the anterior pituitary, and so was known as FSH-suppressing protein (FSP). Since then its primary function has been determined to be the binding and bioneutralization agent of members of the TGF-β superfamily, with primary focus on activin, a paracrine hormone (TGF-β member) which enhances secretion of FSH in the anterior pituitary.
Follistatin and BMPs are also known to play a role in folliculogenesis within the ovary. The main role of follistatin in the oestrus/menstrus ovary, so far, appears to be progression of the follicle from early antral to antral/dominant, and importantly the promotion of cellular differentiation of the estrogen producing granulosa cells (GC) of the dominant follicle into the progesterone producing large lutein cells (LLC) of the corpus luteum.
Follistatin is being studied for its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive muscle growth. Lee & McPherron demonstrated that inhibition of GDF-8, either by genetic elimination (knockout mice) or by increasing the amount of follistatin, resulted in greatly increased muscle mass. In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength. This research paves the way for human clinical trials, which are hoped to begin in the summer of 2010 on Inclusion body myositis.
A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy (SMA) in animal models.
It is also being investigated for its involvement in polycystic ovary syndrome (PCOS), though there is debate as to its direct role in this infertility disease.It is also being investigated for its involvement in polycystic ovary syndrome (PCOS), though there is debate as to its direct role in this infertility disease.
Follistatin and Muscle Growth:
Follistatin works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth. It’s also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow.
The recent increase in attention in the science community on follistatin and other myostatin inhibitors is primarily due to the desire to find an alternative means to treat muscle disorders; the most popular current option is androgen steroids which pose a number of side-effects and long-term health risks. At this point you might be wondering why follistatin use isn’t more widespread in bodybuilders and other athletes. In the next section we will examine the current research on follistatin and whether it builds muscle mass.
|Best prices.||High quality doesn't mean expensiveness. Products we offer are made in China, so they are much cheaper than Genotropin or Humatrope produced in Europe and the USA due to low manufacturing expenses in China. Most of our customers are bodybuilders and they don't need to spend 500-800 $ for 100 IU of Genotropin, you will get equal quality 2-3 times cheaper.|
|Storage conditions.||Produced using liophilisation technology (freeze-drying) and vials are vacuum-packed - that's why our products can be stored outside the fridge without any damage to product.|
|GMP certification.||GMP is the most trusted system of medicine certification.|
|Express delivery.||As you know this products is a fragile substance and need to be delivered quickly. We use various express to deliver to your door within 3-7 workdays as sooner as we can.|
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|We ship worldwide.|
|VERY discreet packaging.||We pack very discreetly and never mention pharmaceutical content inside. For this reason, until now we have almost ZERO seizures delivering till now.|
|Free reship in the case of seizure. Although we have very high success delivery rate - 100 % to the US and UK and 98 % to Europe, we will reship your package for free if it's seized by customs.|
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