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GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome

GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome

    • GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome
    • GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome
    • GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome
    • GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome
  • GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome

    Product Details:

    Place of Origin: Hubei, China
    Brand Name: Bodybiological
    Certification: ISO9001, SGS
    Model Number: CAS: 98319-26-7

    Payment & Shipping Terms:

    Minimum Order Quantity: 10gram
    Price: USD2/gram
    Packaging Details: Foil bag
    Delivery Time: Within 24 hours
    Payment Terms: T/T, Western Union, MoneyGram
    Supply Ability: 100kg/month
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    Detailed Product Description
    Keywords: Tibolone Appearance: Yellow Powder
    Shipping Method: FEDEX, TNT, DHL, UPS, HK EMS Payment Terms: Money Gram, Western Union, Bank Transfer
    Export Market: USA, UK, Canada, Thailand, Brazil Purity: 99%
    Policy: Reshipping Policy Brand: Bodybiological

    GMP Grade Fitness Building Tibolone Acetate for Menopausal Syndrome

     

    Basic information:

     

    Synonyms:LIVIELLA; LIVIAL
    Quick Detail:
    CAS: 5630-53-5
    EINECS: 227-069-1
    Molecular Formula: C21H28O2
    Molecular weight: 312.45
    Melting Point: 169°C
    Character: White powder.
    Delivery: Express courier.
    Usage: Pharmaceutical material

     

    Detailed information:

     

    Tibolone (INN, USAN, BAN) (brand name Livial, Tibofem), also known as 7α-methylnoretynodrel,[1] is a synthetic steroid drug with estrogenic, progestogenic, and weak androgenic actions which was introduced in 1988 and is used widely in Europe, Asia, Australasia, and, with the exception of the United States (where it is not available), the rest of the world.[2][3][4][5] It is used mainly for treatment of endometriosis,[6] as well as hormone replacement therapy in post-menopausal women. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile.[7][8][9] It has also been investigated as a possible treatment for female sexual dysfunction.

     

    Applications:

     

    Tibolone possesses a complex pharmacology.[14] Its two major active metabolites, 3α-hydroxytibolone and 3β-hydroxytibolone, act as potent, fully activating agonists of the estrogen receptor (ER), with a high preference for ERα.[14][15][16] Tibolone and its metabolite Δ4-tibolone act as agonists of the progesterone and androgen receptors,[15] while 3α-hydroxytibolone and 3β-hydroxytibolone, conversely, act as antagonists of these receptors.[14] Lastly, tibolone, 3α-hydroxytibolone, and 3β-hydroxytibolone act as antagonists of the glucocorticoid and mineralocorticoid receptors, with preference for the mineralocorticoid receptor.[14]

    Tibolone has tissue-selective estrogenic effects, with desirable effects in bone, the brain, and the vagina, and lack of undesirable action in the endometrium and breasts.[16] Its tissue selectivity is the result of metabolism, enzyme modulation (e.g., of estrogen sulfatase and estrogen sulfotransferase), and receptor modulation that vary in different target tissues, and differs mechanistically from that of selective estrogen receptor modulators (SERMs) such as tamoxifen, which produce their tissue-selectivity via means of modulation of the ER.[15][16] As such, to distinguish it from SERMs, tibolone has been described as a "selective tissue estrogenic activity regulator" (STEAR),[16] and also as a "selective estrogen enzyme modulator"

     

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    GMP Grade Tren Anabolic Steroid Fitness Building Tibolone For Menopausal Syndrome

    Contact Details
    Wuhan Body Biological Co.,Ltd

    Contact Person: Clare

    Tel: +8618271632602

    Send your inquiry directly to us (0 / 3000)

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