|Room 4331, 3th building, high-tech industrial park, yizhi road, qingshan district, wuhan, China||Body@bodybiological.com|
|Place of Origin:||China, Hubei|
|Model Number:||CAS: 6108-05-0|
|Minimum Order Quantity:||1kg|
|Delivery Time:||Within 24 hours after the payment|
|Payment Terms:||T/T, Western Union, MoneyGram|
|Policy:||Resend Policy||Shipping Way:||FEDEX,DHL,TNT,HK EMS, Airmail...|
|Appearance:||White Crystalline Powder||Molecular Formula:||C14H22N2O|
|Delivery Time:||Within 24 Hours Upon Receipt Of Payment||Product Name:||Lidocaine HCL|
|Usage:||Topically Used To Relieve Itching, Burning, And Pain From Skin Inflammations, Injected As A Dental Anesthetic, Or As A Local Anesthetic For Minor Surgery||CAS:||6108-05-0|
White Crystalline Pharmaceuticals Raw Powder Lidocaine Hydrochloride for Sale
Lidocaine Base CAS: 137-58-6
Product Name: Lidocaine Base
Synonyms: 2-(Diethylamino)-N-(2, 6-dimethylphenyl)-acetamide; Lignocaine; 2-diethylaminoacet-2, 6-xylidide; Lidocaine; Xylocaine; N-(2, 6-dimethylphenyl)-N~2~, N~2~-diethylglycinamide; 2-[(2, 6-dimethylphenyl)amino]-N, N-diethyl-2-oxoethanaminium
CAS Registry Number: 137-58-6
Molecular Formula: C14H23N2O
Molecular Weight: 235.3447
Appearance: White Crystalline Powder
Lidocaine, xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system.
Lidocaine is the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.
Drug Class And Mechanism:
Lidocaine is an antiarrhythmic agent (affects heart rhythm) as well as a local anesthetic (amide type). It is similar to bupivacaine and procaine. Lidocaine, like other local anesthetics causes a loss of sensation by reducing the flow of sodium in and out nerves to decrease the initiation and transfer of nerve signals. Compared to procaine, lidocaine has a more rapid onset, longer duration of action, and more potent activity. Lidocaine works as an antiarrhythmic by also decreasing conduction of electrical signals in damaged (ischemic) heart tissue. Lidocaine was approved by the FDA in November 1948.
Lidocaine alters signal conduction in neurons by blocking the fast voltage-gated Na+ channels in the neuronal cell membrane responsible for signal propagation. With sufficient blockage, the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain, but by stopping them before they begin. Careful titration allows for a high degree of selectivity in the blockage of sensory neurons, whereas higher concentrations also affect other modalities of neuron signaling.
The same principle applies for this drug's actions in the heart. Blocking sodium channels in the conduction system, as well as the muscle cells of the heart, raises the depolarization threshold, making the heart less likely to initiate or conduct early action potentials that may cause an arrhythmia.
|Other Name||2-(Diethylamino)-N-(2,6-dimethylphenyl) acetamide|
|Color||White crystalline powder||Cas No.||137-58-6|
|Molecular Formula||C14H22N2O||Molecular Weight||234.34|
|Main functions are as follows:|
|Function||1. Local anesthetic.|
|2. Treating Epilepsy.|
|3. Treating Asthma.|
|Applications||Main applications are as follows:|
|Applied in pharmaceuticalfields.|
|Storage||Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.|
|Characters||White or slightly yellow crystal powder with characteristic odor||White crystal powder with weak odor|
|Melting point||Melting point: 66 degree to 70 degree||66.6 degree-68.5 degree|
|Comply with the requirement|
|Appearance of solution||Clear and colorless||Conforms|
|Water||Not more than 0.5%||0.30%|
|Sulphate||Not more than0. 1%||Conforms|
|Chloride||Not more than 0. 0035%||0.00%|
|Heavy Metals||Not more than 0.002%||0.00%|
|Residue on Ignition||Not more than 0.1%||0.02%|
|Impurity||Not more than 0.01%||Conforms|
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