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CAS 6108-05-0 White Pharmaceuticals Raw Materials powder Lidocaine Hydrochloride

CAS 6108-05-0 White Pharmaceuticals Raw Materials powder Lidocaine Hydrochloride

    • CAS 6108-05-0 White Pharmaceuticals Raw Materials powder Lidocaine Hydrochloride
    • CAS 6108-05-0 White Pharmaceuticals Raw Materials powder Lidocaine Hydrochloride
    • CAS 6108-05-0 White Pharmaceuticals Raw Materials powder Lidocaine Hydrochloride
    • CAS 6108-05-0 White Pharmaceuticals Raw Materials powder Lidocaine Hydrochloride
  • CAS 6108-05-0 White Pharmaceuticals Raw Materials powder Lidocaine Hydrochloride

    Product Details:

    Place of Origin: China, Hubei
    Brand Name: Bodybiological
    Certification: ISO9001,SGS
    Model Number: CAS: 6108-05-0

    Payment & Shipping Terms:

    Minimum Order Quantity: 1kg
    Price: USD10
    Packaging Details: 25kg/drum
    Delivery Time: Within 24 hours after the payment
    Payment Terms: T/T, Western Union, MoneyGram
    Supply Ability: 1000kg/month
    Contact Now
    Detailed Product Description
    Packing: 25kg/drum Purity: 99.5%
    Policy: Resend Policy Shipping Way: FEDEX,DHL,TNT,HK EMS, Airmail...
    Appearance: White Crystalline Powder Molecular Formula: C14H22N2O
    Delivery Time: Within 24 Hours Upon Receipt Of Payment Product Name: Lidocaine HCL
    Usage: Topically Used To Relieve Itching, Burning, And Pain From Skin Inflammations, Injected As A Dental Anesthetic, Or As A Local Anesthetic For Minor Surgery CAS: 6108-05-0

    White Crystalline Pharmaceuticals Raw Powder Lidocaine Hydrochloride for Sale

     

    Quick details:

     

    Lidocaine Base CAS: 137-58-6
    Product Name: Lidocaine Base
    Synonyms: 2-(Diethylamino)-N-(2, 6-dimethylphenyl)-acetamide; Lignocaine; 2-diethylaminoacet-2, 6-xylidide; Lidocaine; Xylocaine; N-(2, 6-dimethylphenyl)-N~2~, N~2~-diethylglycinamide; 2-[(2, 6-dimethylphenyl)amino]-N, N-diethyl-2-oxoethanaminium
    CAS Registry Number: 137-58-6
    Assays: 99%
    Packaging: 25kg/drum
    Molecular Formula: C14H23N2O
    Molecular Weight: 235.3447
    EINECS: 205-302-8
    Appearance: White Crystalline Powder

     

    Description:

     

    Lidocaine, xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system.
    Lidocaine is the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.

     

    Applications:

     

    • This medication is used on the skin to stop itching and pain from certain skin conditions (e.g., scrapes, minor burns, eczema, insect bites) and to treat minor discomfort and itching caused by hemorrhoids and certain other problems of the genital/anal area (e.g., anal fissures, itching around the vagina/rectum). Some forms of this medication are also used to decrease discomfort or pain during certain medical procedures/exams (e.g., sigmoidoscopy, cystoscopy). Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.
    • Local anesthesic;Na+ channel blocker
    • Anesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic.

     

    Drug Class And Mechanism:

     

    Lidocaine is an antiarrhythmic agent (affects heart rhythm) as well as a local anesthetic (amide type). It is similar to bupivacaine and procaine. Lidocaine, like other local anesthetics causes a loss of sensation by reducing the flow of sodium in and out nerves to decrease the initiation and transfer of nerve signals. Compared to procaine, lidocaine has a more rapid onset, longer duration of action, and more potent activity. Lidocaine works as an antiarrhythmic by also decreasing conduction of electrical signals in damaged (ischemic) heart tissue. Lidocaine was approved by the FDA in November 1948.

     

    Pharmacodynamics:

     

    (1) Anaesthesia


    Lidocaine alters signal conduction in neurons by blocking the fast voltage-gated Na+ channels in the neuronal cell membrane responsible for signal propagation. With sufficient blockage, the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain, but by stopping them before they begin. Careful titration allows for a high degree of selectivity in the blockage of sensory neurons, whereas higher concentrations also affect other modalities of neuron signaling.


    (2) Antiarrhythmic


    The same principle applies for this drug's actions in the heart. Blocking sodium channels in the conduction system, as well as the muscle cells of the heart, raises the depolarization threshold, making the heart less likely to initiate or conduct early action potentials that may cause an arrhythmia.

     

    COA :

     

    Product Name Lidocaine
    Other Name 2-(Diethylamino)-N-(2,6-dimethylphenyl) acetamide
    Assay (%) ≥99.5 Odor Characteristic
    Color White crystalline powder Cas No. 137-58-6
    Molecular Formula C14H22N2O Molecular Weight 234.34
    Standard USP30
      Main functions are as follows:
    Function 1. Local anesthetic.
      2. Treating Epilepsy.
      3. Treating Asthma.
    Applications Main applications are as follows:
      Applied in pharmaceuticalfields.
    Packing 25kg/drum
    Storage Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
    Items Tested Specification BP2007 Result
    Characters White or slightly yellow crystal powder with characteristic odor White crystal powder with weak odor
    Melting point Melting point: 66 degree to 70 degree 66.6 degree-68.5 degree
    Identification BCDE Conforms
      Comply with the requirement  
    Appearance of solution Clear and colorless Conforms
    Water Not more than 0.5% 0.30%
    Sulphate Not more than0. 1% Conforms
    Chloride Not more than 0. 0035% 0.00%
    Heavy Metals Not more than 0.002% 0.00%
    Residue on Ignition Not more than 0.1% 0.02%
    Impurity Not more than 0.01% Conforms
    (26-dimethylaniline content)    
    Assay (HPLC) 99.0%-101.0% 99.60%
    Conclusion Conforms BP2007

     

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    CAS 6108-05-0 White Pharmaceuticals Raw Materials powder Lidocaine Hydrochloride

    Contact Details
    Wuhan Body Biological Co.,Ltd

    Contact Person: Clare

    Tel: +8618271632602

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