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CAS 54965-24-1 Safe Nolvadex Steroid , Fitness White Tamoxifen Citrate Powder

CAS 54965-24-1 Safe Nolvadex Steroid , Fitness White Tamoxifen Citrate Powder

    • CAS 54965-24-1 Safe Nolvadex Steroid , Fitness White Tamoxifen Citrate Powder
    • CAS 54965-24-1 Safe Nolvadex Steroid , Fitness White Tamoxifen Citrate Powder
    • CAS 54965-24-1 Safe Nolvadex Steroid , Fitness White Tamoxifen Citrate Powder
    • CAS 54965-24-1 Safe Nolvadex Steroid , Fitness White Tamoxifen Citrate Powder
  • CAS 54965-24-1 Safe Nolvadex Steroid , Fitness White Tamoxifen Citrate Powder

    Product Details:

    Place of Origin: Hubei, China
    Brand Name: bodybiological
    Certification: ISO9001, SGS
    Model Number: CAS: 54965-24-1

    Payment & Shipping Terms:

    Minimum Order Quantity: 10g and 1vial
    Price: USD1/g
    Packaging Details: Foil bag
    Delivery Time: Within 24 hours after the payment
    Payment Terms: T/T, Western Union, MoneyGram
    Supply Ability: 230kg/Month
    Contact Now
    Detailed Product Description
    Keywords: Tamoxifen Citrate Alias: Nolvadex
    CAS: 54965-24-1 Delivery Time: Within 24 Hours After The Payment
    Shipping Way: FEDEX, TNT, UPS, DHL, Airmail, HK EMS... Payment Terms: Money Gram, Western Union, T/T
    Policy: Resending Policy Appearance: White Powder And Tablets

    CAS 54965-24-1 Safe Nolvadex/Tamoxifen Citrate For Fitness For Weight Loss

     

    Tamoxifen Citrate​ quick details:

     

    Product Name: Tamoxifen Citrate
    Alias: TAM;Nolvadex
    CAS No.: 10540-29-1
    Molecular Formula: C26H29NO 10540-29-1 Tamoxifen Citrate For Men Hair Loss Treatment Nolvadex
    Molecular Weight: 371.51
    Purity: ≥99%
    Appearance: White power .
    Use: Antitumor drugs raw material, suitable for breast cancer.
    Packing: According to customer requirements for packaging

     

    Uses


    Tamoxifen is used to treat breast cancer that has spread to other parts of the body (metastatic breast cancer), to treat breast cancer in certain patients after surgery and radiation therapy, and to reduce the chances of breast cancer in high-risk patients.

    This medication can block the growth of breast cancer. It works by interfering with the effects of estrogen in the breast tissue.

     

    How to use Tamoxifen Citrate


    Read the Medication Guide provided by your pharmacist before you start using tamoxifen and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

    Take this medication by mouth with or without food, usually once or twice daily for 5 years, or as directed by your doctor. Daily dosages greater than 20 milligrams are usually divided in half and taken twice a day, in the morning and evening, or as directed by your doctor. If you are using the liquid, measure the dose carefully using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

     

    Dosage is based on your medical condition and response to therapy.

    Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

    If you have breast cancer that has spread to other parts of the body, you may experience increased bone/cancer pain and/or disease flare-up as you start taking tamoxifen. In some cases, this may be a sign of a good response to the medication. Symptoms include increased bone pain, increased tumor size, or even new tumors. These symptoms usually disappear quickly. In any case, report these symptoms right away to your doctor.

    Since this drug can be absorbed through the skin and lungs, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets. (See also Precautions section.)

    Tamoxifen Citrate
    Class: Antiestrogen

    Trade Names
    Tamoxifen Citrate
    - Tablets, oral 10 mg
    - Tablets, oral 20 mg

     

    Pharmacokinetics


    Absorption
    Tamoxifen C max is 40 ng/mL (range, 35 to 45 ng/mL), T max is approximately 5 h after dosing, and steady state is achieved in approximately 4 wk. N-desmethyl tamoxifen C max is 15 ng/mL (range, 10 to 20 ng/mL). Steady state is achieved in approximately 8 wk.

     

    Metabolism
    Tamoxifen is extensively metabolized. The major metabolite is N-desmethyl tamoxifen with biological activity similar to tamoxifen. It is a substrate of CYP-450 3A, 2C9, 2D6, and an inhibitor of P-glycoprotein.

     

    Elimination
    Tamoxifen half-life is 5 to 7 days; 65% of a dose is excreted over a 2-wk period, with fecal excretion as the primary route of elimination. N-desmethyl tamoxifen half-life is approximately 14 days.

     

    Special Populations
    Hepatic Function Impairment
    The effects of reduced liver function have not been determined.

     

    Elderly
    The effects of age on the pharmacokinetics of tamoxifen have not been determined.

     

    Children
    In pediatric patients, an average steady-state C max and AUC were 187 ng/mL and 4,110 ng•h/mL, respectively, and steady-state C max occurred approximately 8 h after dosing. Cl/F as body weight adjusted in female pediatric patients was approximately 2.3-fold higher than in female breast cancer patients. In the youngest cohort of female pediatric patients (2 to 6 y of age), Cl/F was 2.6-fold higher; in the oldest cohort (7 to 10.9 y of age), Cl/F was approximately 1.9-fold higher.

     

    Gender
    The effects of gender on the pharmacokinetics of tamoxifen have not been determined.

     

    Race
    The effects of race on the pharmacokinetics of tamoxifen have not been determined.

     

    Indications and Usage


    For the treatment of node-positive breast cancer in postmenopausal women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation; for the treatment of axillary node-negative breast cancer in women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation; in women with ductal carcinoma in situ (DCIS) following breast surgery and radiation to reduce the risk of invasive breast cancer; treatment of metastatic breast cancer in women and men; to reduce the incidence of breast cancer in women at high risk of breast cancer.

     

    Unlabeled Uses


    Ovulation stimulation in specially selected anovulatory women desiring pregnancy; management and treatment of some types of mastalgia (eg, cyclical); malignant carcinoid tumor and carcinoid syndrome; migraine associated with menstruation; oligozoospermia; McCune-Albright syndrome in female pediatric patients (in combination with other agents); metastatic melanoma; desmoid tumors; gynecomastia.

     

    Contraindications


    Hypersensitivity to drug; women who require concomitant coumarin-type anticoagulant therapy or women with a history of deep vein thrombosis (DVT) or pulmonary embolus (PE) (reduction of breast cancer incidence in high-risk women/DCIS only).

     

    Dosage and Administration
    Breast Cancer
    Adults
    PO 20 to 40 mg daily for 5 y.

    Ductal Carcinoma In Situ, Reduction in Breast Cancer Incidence in High-Risk Women
    Adults
    PO 20 mg daily for 5 y.

    General Advice
    Divide dosages greater than 20 mg/day (morning and evening).
    Storage/Stability
    Store between 68° and 77°F. Protect from light.

    Drug Interactions
    Aminoglutethimide
    Tamoxifen concentrations may be reduced. Coadministration is not recommended.

    Anastrozole
    Plasma concentrations of anastrozole may be decreased. Do not coadminister.

    Bromocriptine
    Tamoxifen concentrations may be increased. An addition, bromocriptine GI adverse reactions (eg, abdominal pain) may be increased. Avoid coadministration if serious bromocriptine adverse reactions occur.

    Cation exchange resins (eg, sodium polystyrene sulfonate)
    Coadministration of cation exchange resins and tamoxifen may cause serious GI adverse events such as colonic necrosis. Coadministration is not recommended.

     

    CAS 54965-24-1 Safe Nolvadex Steroid , Fitness White Tamoxifen Citrate Powder

    Contact Details
    Wuhan Body Biological Co.,Ltd

    Contact Person: Penny

    Tel: +8613429837396

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