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Injection Recombinant Hematopoietin EPO for Red Blood Cell Production Control

Injection Recombinant Hematopoietin EPO for Red Blood Cell Production Control

  • Injection Recombinant Hematopoietin EPO for Red Blood Cell Production Control
  • Injection Recombinant Hematopoietin EPO for Red Blood Cell Production Control
  • Injection Recombinant Hematopoietin EPO for Red Blood Cell Production Control
  • Injection Recombinant Hematopoietin EPO for Red Blood Cell Production Control
Injection Recombinant Hematopoietin EPO for Red Blood Cell Production Control
Product Details:
Place of Origin: Hubei, China
Brand Name: Bodybiological
Certification: ISO9001, SGS
Model Number: CAS 88431-47-4
Payment & Shipping Terms:
Minimum Order Quantity: 1kit
Price: USD30/kit
Packaging Details: Foil bag
Delivery Time: 3-7 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 600kits/month
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Detailed Product Description
Keywords: Erythropoietin Alias: EPO
Appearance: Freezed-fried Powder Specification: 3000iu/vial 5vials/kit
Shipping Method: FEDEX, TNT, DHL, UPS, HK EMS Payment Terms: Money Gram, Western Union, Bank Transfer
MOQ: 1kit Purity: 99.8%
Export Market: USA, UK, Brazil, Thailand, Canada Brand: Bodybiological
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Injection Recombinant Hematopoietin EPO for Red Blood Cell Production Control

 

Product Details:

 

Customized: Customized
Suitable for: Elderly, Children, Adult, Bodybuilder and Reseller
Purity: >99%
Appearence: White Lyophilized Peptide Powder
Shipment: EMS, TNT, FedEx, DHL, Eub, HK Post
Delivery Time: 3~7 working days
Epo Mf: C18h30o2
Transport Package: Stealth Packing 100% Pass
Origin: Shhanghai, China
Powder: Yes
Certification: GMP, ISO 9001, USP, Ce
State: Solid
Brand Name: Epo 3000iu
Stock: Fresh and Adequate
MOQ: 1kit
Epo MW: 278.43
Full Name: Erythropoietin
Specification: 3000iu/vial, vials/kit
HS Code: 2937004188

 

History:

 

In 1906, Paul Carnot, a professor of medicine in Paris, France, and his assistant, DeFlandres, proposed the idea that hormones regulate the production of red blood cells. After conducting experiments on rabbits subject to bloodletting, Carnot and DeFlandre attributed an increase in red blood cells in rabbit subjects to a hemotropic factor called hemopoietin. Eva Bonsdorff and Eeva Jalavisto continued to study red cell production and later called the hemopoietic substance ‘erythropoietin’. Further studies investigating the existence of EPO by Reissman and Erslev demonstrated that a certain substance, circulated in the blood, is able to stimulate red blood cell production and increase hematocrit. This substance was finally purified and confirmed as erythropoietin, opening doors to therapeutic uses for EPO in diseases like anemia.

In the 1980s, Adamson, Joseph W. Eschbach, Joan C. Egrie, Michael R. Downing and Jeffrey K. Browne conducted a clinical trial at the Northwest Kidney Centers for a synthetic form of the hormone, Epogen produced by Amgen. The trial was successful, and the results were published in the New England Journal of Medicine in January 1987.

In 1985, Lin et al. isolated the human erythropoietin gene from a genomic phage library and were able to characterize it for research and production. Their research demonstrated that the gene for erythropoietin encoded the production of EPO in mammalian cells that is biologically active in vitro and in vivo. The industrial production of recombinant human erythropoietin (RhEpo) for treating anemia patients would begin soon after.

 

Description:

 

Erythropoietin, or its alternative erythropoetin or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow.
Also called hematopoietin or hemopoietin, it is produced by the peritubular capillary endothelial cells in the kidney, and is the hormone that regulates red blood cell production. It also has other known biological functions. For example, erythropoietin plays an important role in the brain's response to neuronal injury. EPO is also involved in the wound healing process.
When exogenous EPO is used as a performance-enhancing drug, it is classified as an erythropoiesis-stimulating agent (ESA). Exogenous EPO can often be detected in blood, due to slight difference from the endogenous protein, for example in features of posttranslational modification.

 

Application:

 

Increasing the number of red blood cells increases the oxygen capacity of the blood to deliver more oxygen for muscle trainingThese advantages led to the widespread use of synthetic doping-dependent p-REPO preparations.
In connection with the increase in oxygen capacity and other vasoactive effects of interest, the EPO has also become interested in athletes outside the crowd of endurance; Including bodybuilders who want to increase the intensity of exercise, the amount of training sessions and the quality of their training, as well as those who are equally interested in achieving the "eternal pump".

 

COA:

 

Name of product Testosterone Enanthate Report NO. 1707-06
Lot NO. 20140706 Manufacture Date 2017.07.14
Package 25kg/Drum Report Date 2017.07.18
Batch size 150Kg Retest Date 2019.07.13
ANALYTICAL ITEMS SPECIFICATION ANALYTICAL RESULTS
Appearance White crystalline powder White crystalline powder
Specific rotation +77 ~ +82 +78
Melting range 34~ 39 34~ 39
Related substances A single impurity≤1.0% 0.0095
Total impurities≤2.0% 0.0155
Waters ≤0.5% 0.30%
Assay 97.0~103.0% 99.62%
Conclusion The specification conform with USP34 standard

 

Indications:

 

Treatment of anemia of chronic renal failure patients, including patients on dialysis and patients not on dialysis.
Treatment of anemia in cancer patients on chemotherapy.
Reduction of allogeneic blood transfusion in surgery patients.

 

Primary role in red cell blood line:

 

Erythropoietin has its primary effect on red blood cells by promoting red blood cell survival through protecting these cells from apoptosis. It also cooperates with various growth factors involved in the development of precursor red cells. Specifically, the colony forming unit-erythroid (CFU-E) is completely dependent on erythropoietin. The burst forming unit-erythroid (BFU-E) is also responsive to erythropoietin.
Under hypoxic conditions, the kidney will produce and secrete erythropoietin to increase the production of red blood cells by targeting CFU-E, pro-erythroblast and basophilic erythroblast subsets in the differentiation.
It has a range of actions including vasoconstriction-dependent hypertension, stimulating angiogenesis, and inducing proliferation of smooth muscle fibers. It has also been shown that erythropoietin can increase iron absorption by suppressing the hormone hepcidin.

 

Injection Recombinant Hematopoietin EPO for Red Blood Cell Production Control 0

 

Our advantage:

 

1. Good quality can be tested .
1) Good quality is the basic of our goal.
2) We can offer samples to be tested.


2. Good feedback.
1) We are a high-tech company in China for many years.
2) 98% of our products have exported to UK, USA, Germany, Spain, Australia, Middle East and many other countries. and we have got very good feedback from our customers.


3. Safe and fast delivery.
1) We have stock, so parcel can be sent out in 24 hours after payment. Tracking number is available.
2) Customs pass rate ≥ 99%


4. Good after-sales service.
Tell the package update ASAP, and will try best solve when customer encountered various problems.

Contact Details
Wuhan Body Biological Co.,Ltd

Contact Person: Clare

Tel: +8618271632602

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