Room 4331, 3th building, high-tech industrial park, yizhi road, qingshan district, wuhan, China | Body@bodybiological.com |
Place of Origin: | Hubei, china |
Brand Name: | Bodybiological |
Certification: | IS09001, SGS |
Minimum Order Quantity: | 1kit |
---|---|
Price: | USD28/kit |
Packaging Details: | Foil bag |
Delivery Time: | 5-7 days |
Payment Terms: | T/T, Western Union, MoneyGram |
Supply Ability: | 800kits/month |
Keywords: | GDF-8 | Appearance: | White Powder |
---|---|---|---|
Shipping Method: | FEDEX, TNT, UPS, DHL, HK EMS | Payment Terms: | Money Gram, Western Union, Bank Transfer |
MOQ: | 1kit | Specification: | 5mg/vial 10vials/kit |
Puirty: | 99.68% | Policy: | Resending Policy |
State: | Powder | Brand: | Bodybiological |
High Light: | research chemicals peptides,muscle growth peptides |
Antibody Myostatin Human Growth Peptide GDF-8/ GDF-8 for Adult
Quick Detail:
Product name:Myostatin GDF-8
Purity:95%
Specification:1mg/vial
Appearance:White powder
Certificate:GMP
Storage:Dry Cool Place
Grade:Medicine Grad
Detailed description:
Regulatory factors that determine actual cell size and number are relatively unknown. It has been suggested that tissues regulate their own size by synthesizing "inhibitors" that feedback on individual cells. When the collective concentration of tissue-specific inhibitor reaches a critical level, tissue-specific cells are frozen in size and number. It has also been proposed that cells outside the tissue of interest, clear or non-functionally bind circulating inhibitor. Thus, the proportion of cells secreting "inhibitor" relative to all cells making up the organism determines the availability of any limiting factor. The larger the quantity of tissue secreting inhibitor, the more inhibitor available to the secreting tissue after body-wide clearance.
One tissue that appears to support the theory of growth inhibition is skeletal muscle. Initial interest in myostatin (or GDF-8; growth/differentiation factor 8) as an inhibitor of skeletal muscle was based on the observation that the GDF-8 gene in double-muscled Belgian Blue and Piedmontese cattle was mutated, thus creating a non-functional protein.1,2 In Belgian Blue cattle, the gene for GDF-8 codes for a mature GDF-8 that is less than 10 amino acids (aa) long; in Piedmontese cattle, a critical cysteine is lost, resulting in a misfolded molecule.2 Recent studies in mice have confirmed the initial observations in cattle; a GDF-8 null mouse results in a super-muscular animal with abnormal muscle mass.3-5 Experiments have also shown that a functional GDF-8 inhibits the growth and proliferation of mouse C2C12 skeletal muscle cells.6,7 GDF-8 is a member of the TGF-beta superfamily (TGF-beta SF), demonstrating a characteristic cysteine knot configuration with extremely high aa conservation across species.2,4,8-11 Like all TGF-beta SF members, GDF-8 is synthesized as a pre-proprotein that undergoes intracellular proteolytic cleavage to create a 109 aa, 24-30 kDa mature, disulfide-linked dimer.4,6,10,12,13 Unlike most members of the TGF-beta SF, the mature GDF-8 dimer is secreted as a latent complex, retaining its pro-region in a non-covalent interaction that is analogous to that for TGF-beta 1. This pro-region confers latency on the mature GDF-8 dimer.
Peptide List:
|
|
|
|
|
|
|
|
|
|
|
|
CJC-1295without DAC(CJC-1293) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Contact Person: Clare
Tel: +8618271632602
Weight Loss Test Phen Testosterone Anabolic Steroid 1255-49-8 Testosterone Phenylpropinate
62-90-8 Healthy Testosterone Anabolic Steroid Muscle Building Testosterone Propionate
Muscle Gaining Testosterone Sustanon 250 Powder , Anabolic Weight Loss Testosterone
Nature Testosterone Anabolic Steroid Dianabol Powder For Weight Loss
HCG Human Growth Hormone Peptide 15 Minutes Rapid Pregnancy Test 5000iu / Vial
Effective White Freezed Ansomone Powder , 96827-07-5 Muscle Building Peptides
Injectable Human Growth Hormone Peptide IGF LR3-1 1000mcg / Vial Long-R3 Igtropin
96827-07-5 Getropin , 10iu / Vial Muscle Ehancement Riptropin HGH Supplements
BU Liquid Boldenone Undecylenate , Yellow Color Steroid Injection For Bodybuilding
Masteron Healthy Dromostanolone Propionate For Anti Estrogen Steroids 99% Purity
USP Durabolin Injectable Anabolic Steroids Nandrolone Decanoate Steroid For Weight Loss
CAS 315-37-7 USP Injectable Anabolic Steroids Powder Testosterone Enanthate Steroid