Hair Growth Pharmaceuticals Raw Materials Raw Powder Anti Androgenic Dutasteride

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Basic info:

Product name: Dutasteride
Synonyms: (5alpha, 17beta)-n-{2, 5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide; DUTASTERIDE; (5A, 17)-N-[2, 5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide; Avodart; GI 198745
CAS: 164656-23-9
MF: C27H30F6N2O2
MW: 528.53
Assay: 99%
Color: white powder

Description:

Dutasteride (trademark name Avodart) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Used for benign prostatic hyperplasia; however, it increases the risk of erectile dysfunction and decreased sexual desire.
Dutasteride useful for the symptoms of benign prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate". In those who are being regularly screened 5-alpha-reductase inhibitor (finasteride and dutasteride) reduce the overall risk of being diagnosed with prostate cancer however there is insufficient data to determine if they have an effect on the risk of death and may increase the chance of more serious cases.

Dutasteride is used alone or with another medication (tamsulosin [Flomax]) to treat benign prostatic hyperplasia. Dutasteride is used to treat symptoms of BPH and may reduce the chance of developing acute urinary retention.Dutasteride may also decrease the chance that prostate surgery will be needed.Dutasteride is in a class of medications called 5-alpha reductase inhibitors. It works by blocking the production of a natural substance that enlarges the prostate.
This medication is used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It works by reducing the size of the enlarged prostate. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate frequently or urgently (including during the middle of the night). It may also reduce the need for surgery to treat BPH.

Application:

Dutasteride prevents the conversion of testosterone to dihydrotestosterone in the body. DHT is involved in the development of benign prostatic hyperplasia .
Dutasteride is used to treat benign prostatic hyperplasia in men with an enlarged prostate. Dutasteride helps improve urinary flow and may also reduce your need for prostate surgery later on.Dutasteride is sometimes given with another medication called tamsulosin. Be sure to read the medication guide or patient instructions provided with each of your medications.
Dutasteride is used to treat enlarged prostate (benign prostatic hyperplasia [BPH]) in men with an enlarged prostate. It helps decrease your risk of a complete blockage of urine flow (acute urinary retention).
This drug can be as an alternative to surgery for men who are uncomfortable with undergoing surgery.
Dutasteride is used by men only.

COA:

Used for:

Treating symptoms of benign prostatic hyperplasia (BPH) or enlargement of the prostate gland. It also helps to reduce the risk of urinary blockage and the need for surgery to treat BPH. It may be used alone or along with another medicine (tamsulosin).
Dutasteride is a 5 alpha-reductase enzyme inhibitor. It works by lowering levels of a hormone called dihydrotestosterone (DHT), which is a major cause of prostate growth. Lowering DHT leads to shrinkage of the enlarged prostate gland.

Don't use dutasteride if:

You are allergic to any ingredient in dutasteride or to another 5 alpha-reductase inhibitor (eg, finasteride)
the patient is a woman who is pregnant or may become pregnant
the patient is a child
Contact your doctor or health care provider right away if any of these apply to you.

How to use dutasteride:

Use dutasteride as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with dutasteride. Talk to your pharmacist if you have questions about this information.
Take dutasteride by mouth with or without food.
Swallow dutasteride whole. Do not break, crush, chew, or open before swallowing. Do not take capsules that are cracked, deformed, discolored, or leaking. Dutasteride can irritate your lips, mouth, and throat.
Take dutasteride on a regular schedule to get the most benefit from it. Taking dutasteride at the same time each day will help you remember to take it.
Continue to take dutasteride even if you feel well. Do not miss any doses.
If you miss a dose of dutasteride, take it as soon as possible if you remember the same day. Skip the missed dose if you do not remember until the next day. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use dutasteride.

Contraindications:

Children, women who are or who may become pregnant, and people with known significant hypersensitivity (e.g., serious skin reactions, angioedema) to dutasteride or finasteride should not take dutasteride. Exposure to dutasteride and other 5α-reductase inhibitors during pregnancy can cause birth defects. Since these medications are readily absorbed through the skin, women who are or may become pregnant should not handle them and if they come into contact with leaking capsules, the contact area should be washed immediately in soapy water. People taking dutasteride should not donate blood and, due to its long half-life, should also not donate blood for at least 6 months after the cessation of treatment.